TY - JOUR
PY - 2016//
TI - A new experimental burn model with an infrared heater
JO - Ulusal travma ve acil cerrahi dergisi
A1 - Güzey, Serbülent
A1 - Dal, Ahmet Demirhan
A1 - Sahin, Ismail
A1 - Nışancı, Mustafa
A1 - Yavan, İbrahim
SP - 412
EP - 416
VL - 22
IS - 5
N2 - BACKGROUND: This study was undertaken to develop new experimental burn injury model using conventional infrared heaters.
METHODS: 21 Sprague-Dawley rats were divided into 3 groups. Portion of dorsal area was exposed to infrared radiation from distance of 50 cm to create burn injury. Length of exposure to heat for Group 1 was 5 minutes; Group 2 was exposed for 7½ minutes, and Group 3 was exposed for 10 minutes. Macroscopic and histopathological evaluations were utilized to demonstrate depth and characteristics of injury.
RESULTS: There was no burn injury in first group. Group 2 developed partial thickness burn, and result was full thickness burn injury in Group 3. In Groups 2 and 3 there was statistically significant difference in dermal collagen denaturation. Dermal injury depth was statistically significantly higher in Group 3 compared to Group 2.
CONCLUSION: New experimental burn injury model is described using conventional infrared heaters. Standard variables pertaining to model were defined to produce burn injuries at predictable depth: 10 minutes of exposure from 50 cm distance for full thickness burn, and 7½ minutes of exposure from the same distance for partial thickness injury.
Language: en
LA - en SN - 1306-696X UR - http://dx.doi.org/ ID - ref1 ER -