TY - JOUR PY - 2016// TI - Association of functional impairments and co-morbid conditions with driving performance among cognitively normal older adults JO - PLoS one A1 - Carr, David B. A1 - Barco, Peggy P. A1 - Babulal, Ganesh M. A1 - Stout, Sarah H. A1 - Johnson, Anne M. A1 - Xiong, Chengjie A1 - Morris, John C. A1 - Roe, Catherine M. SP - e0167751 EP - e0167751 VL - 11 IS - 12 N2 - OBJECTIVES: To examine the relationship between key functional impairments, co-morbid conditions and driving performance in a sample of cognitively normal older adults.

DESIGN: Prospective observational study. SETTING: The Knight Alzheimer's Disease Research Center, Washington University at St. Louis. PARTICIPANTS: Individuals with normal cognition, 64.9 to 88.2 years old (N = 129), with a valid driver's license, who were currently driving at least once per week, and who had participated in longitudinal studies at the Knight Alzheimer's Disease Research Center. MEASUREMENTS: Static visual acuity, contrast sensitivity, physical frailty measures, motor skills, total medical conditions, and the modified Washington University Road Test.

RESULTS: When controlling for age, race, gender, APOE, and education the total number of medical conditions was unassociated with both road test scores (pass vs. marginal + fail) and the total driver error count. There were marginal associations of our measure of physical frailty (p = 0.06) and contrast sensitivity score (p = 0.06) with total driving error count.

CONCLUSION: Future research that focuses on older adults and driving should consider adopting measures of physical frailty and contrast sensitivity, especially in samples that may have a propensity for disease impacting visual and/or physical function (e.g. osteoarthritis, Parkinson's, eye disorders, advanced age >80 years, etc.).

Language: en

LA - en SN - 1932-6203 UR - http://dx.doi.org/10.1371/journal.pone.0167751 ID - ref1 ER -