TY  - JOUR
PY  - 2016//
TI  - The Mangled Extremity Score and amputation: time for a revision
JO  - Journal of trauma and acute care surgery
A1  - Loja, Melissa N.
A1  - Sammann, Amanda
A1  - Dubose, Joseph
A1  - Li, Chin-Shang
A1  - Liu, Yu
A1  - Savage, Stephanie
A1  - Scalea, Thomas
A1  - Holcomb, John B.
A1  - Rasmussen, Todd E.
A1  - Knudson, M. Margaret
SP  - 518
EP  - 523
VL  - 82
IS  - 3
N2  - BACKGROUND: The Mangled Extremity Severity Score (MESS) was developed 25 years ago in an attempt to utilize the extent of skeletal and soft tissue injury, limb ischemia, shock, and age to predict the need for amputation after extremity injury. Subsequently, there have been mixed reviews as to the utility of this score. We hypothesized that the MESS, when applied to a data set collected prospectively in modern times, would not correlate with the need for amputation. <br><br>METHODS: We applied the MESS to patient data collected in the American Association for the Surgery of Trauma PROspective Vascular Injury Treatment (PROOVIT) registry. This registry contains prospectively collected demographic, diagnostic, treatment, and outcome data. <br><br>RESULTS: Between 2013 and 2015, 230 patients with lower extremity arterial injuries were entered into the PROOVIT registry. The majority were male with a mean age of 34 years (range 4-92) and a blunt mechanism of injury at a rate of 47.4%. A MESS of 8 or greater was associated with a longer stay in the hospital (median 22.5 (15, 29) vs 12 (6, 21), p=0.006) and ICU (median 6 (2, 13) vs 3 (1, 6), p=0.03). 81.3% of limbs were ultimately salvaged (median MESS 4 (3, 5)) and 18.7% required primary or secondary amputation (median MESS 6 (4, 8), p < 0.001). However, after controlling for confounding variables including mechanism of injury, degree of arterial injury, injury severity score, arterial location, and concomitant injuries, the MESS between salvaged and amputated limbs was no longer significantly different. Importantly, a MESS of 8 predicted in-hospital amputation in only 43.2% of patients. <br><br>CONCLUSION: Therapeutic advances in the treatment of vascular, orthopedic, neurologic and soft tissue injuries have reduced the diagnostic accuracy of the MESS in predicting the need for amputation. There remains a significant need to examine additional predictors of amputation following severe extremity injury. LEVEL OF EVIDENCE: Level III evidence, prospective study, prognostic.<p />  <p>Language: en</p>
LA  - en
SN  - 2163-0755
UR  - http://dx.doi.org/10.1097/TA.0000000000001339
ID  - ref1
ER  -