TY  - JOUR
PY  - 2017//
TI  - Effectiveness of an intervention to prevent frailty in pre-frail community-dwelling older people consulting in primary care: a randomised controlled trial
JO  - Age and ageing
A1  - Serra-Prat, M.
A1  - Sist, X.
A1  - Domenich, R.
A1  - Jurado, L.
A1  - Saiz, A.
A1  - Roces, A.
A1  - Palomera, E.
A1  - Tarradelles, M.
A1  - Papiol, M.
SP  - 401
EP  - 407
VL  - 46
IS  - 3
N2  - BACKGROUND: evidence on the effectiveness of interventions to prevent frailty is scarce. <br><br>OBJECTIVE: to assess the effect of an intervention in preventing frailty progression in pre-frail older people. STUDY DESIGN: a randomised, open label, controlled trial with two parallel arms. POPULATION: community-dwelling pre-frail older people (≥70 years) consulting in primary care. INTERVENTION: nutritional assessment (and derivation to a Nutritional Unit for usual care in the event of nutritional risk) and a physical activity programme including aerobic exercise and a set of mixed strengthening, balance and coordination exercises CONTROL GROUP: patients receiving the usual care. MAIN OUTCOME MEASURE: prevalence of frailty (Fried criteria) at 12 months. SECONDARY OUTCOMES MEASURES: functional capacity (Barthel index), falls and nutritional status (Short-Form Mini Nutritional Assessment) on follow-up at 12 months. <br><br>RESULTS: one hundred and seventy-two participants were recruited and randomised (mean age: 78.3 years; mean number of Fried criteria: 1.45). Thirty-nine participants (22.6%) were dropped out during the study. At follow-up, 4.9% of the intervention group and 15.3% of the control group had evolved to frailty, for a crude odds ratio (OR) of 0.29 (95% confidence interval [CI]: 0.08-1.08; P = 0.052) and an adjusted (by age, gender and number of co-morbidities) OR of 0.19 (95% CI: 0.04-0.95; P = 0.044). Intervention group showed a higher outdoors walking hour per day (0.97 versus 0.73; P = 0.019) but no difference was observed in muscle strength, gait speed or other functional indicators. <br><br>CONCLUSION: an intervention focused on physical exercise and maintaining good nutritional status may be effective in preventing frailty in community-dwelling pre-frail older individuals. CLINICALTRIALSGOV IDENTIFIER: NCT02138968.<br><br>© The Author 2017. Published by Oxford University Press on behalf of the British Geriatrics Society.All rights reserved. For permissions, please email: journals.permissions@oup.com.<p />  <p>Language: en</p>
LA  - en
SN  - 0002-0729
UR  - http://dx.doi.org/10.1093/ageing/afw242
ID  - ref1
ER  -