TY - JOUR PY - 2017// TI - Comparison of clinical outcomes in diabetic and non-diabetic burns patients in a national burns referral centre in southeast Asia: a 3-year retrospective review JO - Burns: journal of the International Society for Burn Injuries A1 - Low, Zhao-Kai A1 - Ng, Wai-Yee A1 - Fook-Chong, Stephanie A1 - Tan, Bien-Keem A1 - Chong, Si-Jack A1 - Hwee, Jolie A1 - Tay, Sook-Muay SP - 436 EP - 444 VL - 43 IS - 2 N2 - OBJECTIVE: Diabetic burns patients may be at risk of worse clinical outcomes. This study aims to further investigate the impact of diabetes mellitus on clinical outcomes in burns patients in Singapore.

METHODS: A 3-year retrospective review was performed at the Singapore General Hospital Burns Centre (2011-2013). Pure inhalational burns were excluded. Diabetic (N=53) and non-diabetic (N=533) patients were compared, and the impact of diabetes on clinical outcomes, adjusting for confounders, was investigated using multivariate logistic regression.

RESULTS: The diabetic group had a significantly higher incidence of wound infection and severe renal impairment, as well as a longer length of stay, higher number of operations and higher rate of unplanned readmission. ICU admission was significantly associated with hyperglycaemia (OR 5.44 [2.61-11.35], p<0.001) and a higher total body surface area of burn (OR per 1% TBSA 1.07 [1.05-1.09], p<0.001). Unplanned readmission was significantly associated with wound infection (OR 4.29 [1.70-10.83], p=0.002), and mortality associated with a higher TBSA (OR per 1% TBSA 1.1 [1.07-1.14], p<0.001). After adjusting for confounders, diabetes mellitus was not significantly associated with unplanned readmission or mortality.

CONCLUSIONS: Diabetic burns patients have an increased risk of worse clinical outcomes, including wound infections, renal impairment and longer length of stay.

Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

Language: en

LA - en SN - 0305-4179 UR - http://dx.doi.org/10.1016/j.burns.2016.06.004 ID - ref1 ER -