TY  - JOUR
PY  - 2017//
TI  - Increased risk of suicide in schizophrenia patients with linkage to chromosome 13q
JO  - Psychiatry research
A1  - Malherbe, P. J.
A1  - Karayiorgou, M.
A1  - Ehlers, R.
A1  - Roos, Johannes L.
SP  - 34
EP  - 35
VL  - 251
IS  - 
N2  - We link schizophrenia in families from the genetically isolated South African Afrikaner population to chromosome 13q (n =51), 1p (n =23) and combined 13q & 1p (n =18). Patients with linkages to chromosome 13q were 4.16 times more likely to meet diagnostic criteria for schizoaffective disorder compared to patients with linkage to 1p. A third of patients with linkage to both 13q &1p met diagnostic criteria for SAD. There was a significant positive relationship between suicidality and a diagnosis of schizoaffective disorder. Identifying linkage to chromosome 13q may be informative in identifying suicide risk early and prevent morbidity and mortality in schizophrenia patients.<br><br>Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-1781
UR  - http://dx.doi.org/10.1016/j.psychres.2017.02.008
ID  - ref1
ER  -