TY  - JOUR
PY  - 2017//
TI  - Sleep disorders in spinal muscular atrophy
JO  - Sleep Medicine
A1  - Pera, Maria C.
A1  - Romeo, Domenico M.
A1  - Graziano, Alessandra
A1  - Palermo, Concetta
A1  - Messina, Sonia
A1  - Baranello, Giovanni
A1  - Coratti, Giorgia
A1  - Massaro, Maria
A1  - Sivo, Serena
A1  - Arnoldi, Maria Teresa
A1  - Mazzone, Elena S.
A1  - Antonaci, Laura
A1  - Lapenta, Leonardo
A1  - Albamonte, Emilio
A1  - Fanelli, Lavinia
A1  - de Sanctis, Roberto
A1  - Vita, Gian Luca
A1  - Sframeli, Maria
A1  - Pane, Marika
A1  - Mercuri, Eugenio
SP  - 160
EP  - 163
VL  - 30
IS  - 
N2  - OBJECTIVE: To estimate the frequency of sleep disorders in young persons with type 2 and type 3 spinal muscular atrophy (SMA), and to evaluate the relationship between sleep disorders and different variables such as motor impairment, age, use of ventilation, and use of night orthoses. <br><br>METHODS: A total of 85 young persons (6-25 years of age) with type 2 and type 3 SMA were assessed using the Sleep Disturbance Scale for Children (SDSC), a scale assessing different sleep factors, and the Hammersmith Functional Motor Scale Expanded (HFMSE), a scale evaluating motor impairment. <br><br>RESULTS: An abnormal total sleep score was found in 16.4% of children with SMA; an additional 16.7% had an abnormal score on at least one of the sleep factors assessed by the SDSC. No specific correlation was observed between sleep disturbances and functional level as expressed by the SDSC and total HFMSE scores, but the relationship with individual items on the scale was different. The SDSC total score was significantly associated with the ability to half roll on both sides and to roll from prone to supine on the HMFSE. <br><br>CONCLUSION: Our results demonstrate that sleep disorders are common in children with SMA.<br><br>Copyright © 2016. Published by Elsevier B.V.<p />  <p>Language: en</p>
LA  - en
SN  - 1389-9457
UR  - http://dx.doi.org/10.1016/j.sleep.2016.11.012
ID  - ref1
ER  -