TY - JOUR PY - 2017// TI - Drugs and driving research in medicinal drug development JO - Trends in pharmacological sciences A1 - Ramaekers, J. G. SP - 319 EP - 321 VL - 38 IS - 4 N2 - Medicinal drugs that cause drowsiness and inattentiveness may impair driving. The FDA recently emphasized that standardized procedures for measuring drug effects on driving are needed as part of drug registration. Here, I provide an overview of a standardized on-the-road driving test that offers maximal drug sensitivity and uses a real-life outcome measure of driver impairment that is strongly associated with crash risk.

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Language: en

LA - en SN - 0165-6147 UR - http://dx.doi.org/10.1016/j.tips.2017.01.006 ID - ref1 ER -