TY - JOUR
PY - 2018//
TI - Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)
JO - CNS spectrums
A1 - Dell'osso, Bernardo
A1 - Benatti, Beatrice
A1 - Arici, Chiara
A1 - Palazzo, Carlotta
A1 - Altamura, A. Carlo
A1 - Hollander, Eric
A1 - Fineberg, Naomi
A1 - Stein, Dan J.
A1 - Nicolini, Humberto
A1 - Lanzagorta, Nuria
A1 - Marazziti, Donatella
A1 - Pallanti, Stefano
A1 - Van Ameringen, Michael
A1 - Lochner, Christine
A1 - Karamustafalioglu, Oguz
A1 - Hranov, Luchezar
A1 - Figee, Martijn
A1 - Drummond, Lynne
A1 - Rodriguez, Carolyn I.
A1 - Grant, John
A1 - Denys, Damiaan
A1 - Menchón, Jose M.
A1 - Zohar, Joseph
SP - 59
EP - 66
VL - 23
IS - 1
N2 - OBJECTIVE: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients.
METHODS: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson's chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable.
RESULTS: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables.
CONCLUSIONS: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.
Language: en
LA - en SN - 1092-8529 UR - http://dx.doi.org/10.1017/S1092852917000177 ID - ref1 ER -