TY  - JOUR
PY  - 2017//
TI  - Physiological markers of motor inhibition during human behavior
JO  - Trends in neurosciences
A1  - Duque, Julie
A1  - Greenhouse, Ian
A1  - Labruna, Ludovica
A1  - Ivry, Richard B.
SP  - 219
EP  - 236
VL  - 40
IS  - 4
N2  - Transcranial magnetic stimulation (TMS) studies in humans have shown that many behaviors engage processes that suppress excitability within the corticospinal tract. Inhibition of the motor output pathway has been extensively studied in the context of action stopping, where a planned movement needs to be abruptly aborted. Recent TMS work has also revealed markers of motor inhibition during the preparation of movement. Here, we review the evidence for motor inhibition during action stopping and action preparation, focusing on studies that have used TMS to monitor changes in the excitability of the corticospinal pathway. We discuss how these physiological results have motivated theoretical models of how the brain selects actions, regulates movement initiation and execution, and switches from one state to another.<br><br>Copyright © 2017 Elsevier Ltd. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0166-2236
UR  - http://dx.doi.org/10.1016/j.tins.2017.02.006
ID  - ref1
ER  -