TY  - JOUR
PY  - 2017//
TI  - Associations between childhood maltreatment and non-medical use of prescription drugs among Chinese adolescents
JO  - Addiction
A1  - Guo, Lan
A1  - Xu, Yan
A1  - Deng, Jianxiong
A1  - Gao, Xue
A1  - Huang, Guoliang
A1  - Huang, Jinghui
A1  - Deng, Xueqing
A1  - Zhang, Wei-Hong
A1  - Lu, Ciyong
SP  - 1600
EP  - 1609
VL  - 112
IS  - 9
N2  - AIMS: To test, among Chinese adolescents: (1) whether childhood maltreatment is associated with non-medical use of prescription drugs (NMUPD), (2) whether there are interaction effects of childhood maltreatment and depressive symptoms on NMUPD. <br><br>DESIGN: A secondary analysis of the cross-sectional data collected from 7(th) and 12(th) graders who were sampled using a multistage, stratified cluster, random sampling method in the 2015 School-based Chinese Adolescents Health Survey (SCAHS). SETTING: Surveys conducted in high schools in six cities of China in 2015. PARTICIPANTS: There were 24,457 students who were invited to participate and 23,039 students' questionnaires were completed and qualified for our survey. MEASUREMENTS: The outcomes comprised self-report of NMUPD (prior 30 days); a history of childhood maltreatment was our main predictor; other covariates included depressive symptoms, smoking, drinking, and demographics. Data were analyzed using multi-level regression modeling. <br><br>FINDINGS: Our final multivariable logistic regression models demonstrated that after adjusting for other variables, physical abuse was positively associated with non-medical use of opioids (adjusted odds ratio [AOR] = 1.13, 95% confidence interval [CI] = 1.10-1.22), sedatives (AOR = 1.11, 95% CI = 1.10-1.21), and any prescription drugs (AOR = 1.13, 95% CI = 1.09-1.20); emotional abuse, sexual abuse, and emotional neglect were also associated with an increased risk of opioids misuse, sedatives misuse, and any prescription drugs misuse; students who reported that they had experienced childhood physical neglect were more likely to be involved in the non-medical use of sedatives (AOR = 1.08, 95% CI = 1.04-1.12) and any prescription drugs (AOR = 1.06, 95% CI = 1.03-1.10). Additionally, there was no evidence of interaction effects on NMUPD between depressive symptoms and each of physical abuse, emotional abuse, sexual abuse, physical neglect, and emotional neglect, respectively. . <br><br>CONCLUSIONS: Maltreatment while a child is associated with an increased risk of non-medical use of prescription drugs (NMUPD) among Chinese adolescents. The interactions of maltreatment while a child and depressive symptoms do not appear to be significantly associated with NMUPD among Chinese adolescents.<br><br>This article is protected by copyright. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0965-2140
UR  - http://dx.doi.org/10.1111/add.13850
ID  - ref1
ER  -