TY - JOUR PY - 2016// TI - Extended-release naltrexone to prevent opioid relapse in criminal justice offenders JO - New England journal of medicine A1 - Lee, Joshua D. A1 - Friedmann, Peter D. A1 - Kinlock, Timothy W. A1 - Nunes, Edward V. A1 - Boney, Tamara Y. A1 - Hoskinson, Randall A. Jr. A1 - Wilson, Donna A1 - McDonald, Ryan A1 - Rotrosen, John A1 - Gourevitch, Marc N. A1 - Gordon, Michael A1 - Fishman, Marc A1 - Chen, Donna T. A1 - Bonnie, Richard J. A1 - Cornish, James W. A1 - Murphy, Sean M. A1 - O'Brien, Charles P. SP - 1232 EP - 1242 VL - 374 IS - 13 N2 - Opioid-use disorder is a chronic relapsing condition that has serious public health consequences. Opioid dependence disproportionately affects U.S. criminal justice system populations, and relapse and overdose deaths occur at high rates after release from incarceration.1 Evidence-based opioid-agonist maintenance therapies for opioid dependence (methadone and buprenorphine) are effective in prison, jail, and community reentry (i.e., parole) settings2-5 but have historically been unavailable or discouraged among criminal justice clients.6-8 Extended-release naltrexone (Vivitrol, Alkermes), a sustained-release monthly injectable formulation of the full mu-opioid receptor antagonist, was approved by the Food and Drug Administration in 2010 for the prevention of relapse to. . .
Language: en
LA - en SN - 0028-4793 UR - http://dx.doi.org/10.1056/NEJMoa1505409 ID - ref1 ER -