TY  - JOUR
PY  - 2017//
TI  - Factors associated with participation in an emergency department-based take-home naloxone program for at-risk opioid users
JO  - Annals of emergency medicine
A1  - Kestler, Andrew
A1  - Buxton, Jane
A1  - Meckling, Gray
A1  - Giesler, Amanda
A1  - Lee, Michelle
A1  - Fuller, Kirsten
A1  - Quian, Hong
A1  - Marks, Dalya
A1  - Scheuermeyer, Frank
SP  - 340
EP  - 346
VL  - 69
IS  - 3
N2  - Study objective  Although the World Health Organization recommends take-home naloxone to address the increasing global burden of opioid-related deaths, few emergency departments (EDs) offer a take-home naloxone program. We seek to determine the take-home naloxone acceptance rate among ED patients at high risk of opioid overdose and to examine factors associated with acceptance.   Methods  At a single urban ED, consecutive eligible patients at risk of opioid overdose were invited to complete a survey about opioid use, overdose experience, and take-home naloxone awareness, and then offered take-home naloxone. The primary outcome was acceptance of take-home naloxone, including the kit and standardized patient training. Univariate and multivariable logistic analyses were used to evaluate factors associated with acceptance.   Results  Of 241 eligible patients approached, 201 (83.4%) completed the questionnaire. Three-quarters of respondents used injection drugs, 37% were women, and 26% identified as "Indigenous." Of 201 respondents, 137 (68.2%; 95% confidence interval [CI] 61.7% to 74.7%) accepted take-home naloxone. Multivariable analysis revealed that factors associated with take-home naloxone acceptance included witnessing overdose in others (odds ratio [OR] 4.77; 95% CI 2.25 to 10.09), concern about own overdose death (OR 3.71; 95% CI 1.34 to 10.23), female sex (OR 2.50; 95% CI 1.21 to 5.17), and injection drug use (OR 2.22; 95% CI 1.06 to 4.67).   Conclusion  A two-thirds ED take-home naloxone acceptance rate in patients using opioids should encourage all EDs to dispense take-home naloxone. ED-based take-home naloxone programs have the potential to improve access to take-home naloxone and awareness in individuals most vulnerable to overdoses.<p />  <p>Language: en</p>
LA  - en
SN  - 0196-0644
UR  - http://dx.doi.org/10.1016/j.annemergmed.2016.07.027
ID  - ref1
ER  -