TY - JOUR PY - 2017// TI - Are self-rated and behavioural measures of impulsivity in bipolar disorder mainly related to comorbid substance use problems? JO - Cognitive neuropsychiatry A1 - Bauer, Isabelle E. A1 - Meyer, Thomas D. A1 - Sanches, Marsal A1 - Spiker, Danielle A1 - Zunta-Soares, Giovana A1 - Soares, Jair C. SP - 298 EP - 314 VL - 22 IS - 4 N2 - INTRODUCTION: Impulsivity is a multidimensional feature observed in bipolar disorder (BD) and substance use disorder (SUD). We previously found a relationship between SUD and risk taking in BD. It is still unclear whether self-rated and behavioral impulsivity measures differ between BD with and without comorbid SUD, or are specific to BD.

METHODS: 93 adults with BD with comorbid SUD, 91 BD without SUD, and 93 healthy controls (HC) were administered the Barratt Impulsivity Scale (BIS), the Behavioral Inhibition/Behavioral Activation System Scale (BIS/BAS), and the Cambridge Neuropsychological Test Automated Battery. Analyses compared impulsivity measures across groups controlling for age. Discriminant function analyses (DFA) assessed the combination of variables effectively predicting group membership.

RESULTS: BD displayed increased BIS, BIS/BAS scores, reduced performance on the Cambridge Gambling and Rapid Visual Processing, and Affective Go/No-Go tasks compared to HC. Comparisons between BD with and without SUD showed increased BIS Motor impulsiveness. The overall predictive power of DFA was weak.

CONCLUSIONS: Some facets of impulsivity are a core trait of BD and are partially independent from the presence of SUD. Motor impulsiveness may be distinctive of BD+SUD. More research is needed to understand the role of impulsive behaviors as risk factors for relapse in SUD.

Language: en

LA - en SN - 1354-6805 UR - http://dx.doi.org/10.1080/13546805.2017.1324951 ID - ref1 ER -