TY  - JOUR
PY  - 2017//
TI  - Sleep apnea, disability pension and cause-specific mortality: a nationwide register linkage study
JO  - American journal of epidemiology
A1  - Hulvej Rod, Naja
A1  - Kjeldgård, Linnea
A1  - Akerstedt, Torbjörn
A1  - Ferrie, Jane E.
A1  - Salo, Paula
A1  - Vahtera, Jussi
A1  - Alexanderson, Kristina
SP  - 709
EP  - 718
VL  - 186
IS  - 6
N2  - Sleep apnea is a common problem affecting daily functioning and health. We evaluated associations between sleep apnea and disability pension and mortality in a prospective study of 74,543 cases of sleep apnea (60,125 outpatient; 14,418 inpatient) from the Swedish Patient Register; 2000-2009 inclusive. Cases were matched to five non-cases (n = 371,592) and followed from diagnosis/inclusion via nationwide registers until Dec 31 2010. During a mean (standard deviation) follow-up of 5.1 (2.7) years, 13% men and 21% women with inpatient sleep apnea were disability pensioned. Inpatient sleep apnea was associated with higher total mortality (HR = 1.71; 95% CI: 1.59, 1.84 men; 2.33; 95% CI: 2.04, 2.67 women), with associations strongest for deaths due to ischemic heart disease (HR = 2.27; 95% CI:1.94, 2.65 men; 95% CI: 5.27; 3.78, 7.34 women), respiratory disorders (HR = 3.29; 95% CI: 2.45, 4.42 men; 5.24; 95% CI: 3.52, 7.81 women), and suicide (HR = 1.76; 95% CI: 1.19, 2.60 men; 4.33; 95% CI: 1.96, 9.56 women). There were no associations of inpatient sleep apnea with cancer mortality. Outpatient sleep apnea was associated with higher risk of disability pension, but not higher total mortality. In conclusion, inpatient sleep apnea is related to a higher risk of disability pension and mortality a decade after diagnosis.<br><br>© The Author 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.<p />  <p>Language: en</p>
LA  - en
SN  - 0002-9262
UR  - http://dx.doi.org/10.1093/aje/kwx138
ID  - ref1
ER  -