TY  - JOUR
PY  - 2018//
TI  - Prevalence of externalizing disorders and autism spectrum disorder among children with fetal alcohol spectrum disorder: systematic review and meta-analysis
JO  - Biochemistry and cell biology
A1  - Lange, Shannon
A1  - Rehm, Jürgen
A1  - Anagnostou, Evdokia
A1  - Popova, Svetlana
SP  - 241
EP  - 251
VL  - 96
IS  - 2
N2  - Due to their central nervous system impairments, children with Fetal Alcohol Spectrum Disorder (FASD) commonly exhibit externalizing behaviours such as hyperactivity, impulsivity, and/or delinquency. The purpose of the current study was to estimate the prevalence of neurodevelopmental disorders with prominent externalizing behaviours, namely Attention-Deficit Hyperactivity Disorder (ADHD), Conduct Disorder (CD), Oppositional Defiant Disorder (ODD), as well as Autism Spectrum Disorder (ASD) among children with FASD. A comprehensive systematic literature search was performed, followed by disorder-specific random-effects meta-analyses. Of the disorders investigated, ADHD was found to be the most common co-morbid disorder among children with FASD (52.9%), followed by ODD (12.9%), CD (7.0%), and ASD (2.6%). When compared to the general population of the United States, these rates are notably higher: 15-times higher for ADHD, two-times higher for ASD, three-times higher for CD, and five-times higher for ODD. The results call attention to the need for identifying a distinct neurodevelopmental profile to aid in the accurate identification of children with FASD and the discrimination of FASD from certain idiopathic neurodevelopmental disorders.<p />  <p>Language: en</p>
LA  - en
SN  - 0829-8211
UR  - http://dx.doi.org/10.1139/bcb-2017-0014
ID  - ref1
ER  -