TY  - JOUR
PY  - 1993//
TI  - Buspirone in the management of agitation and aggression associated with dementia
JO  - American journal of geriatric psychiatry
A1  - Herrmann, Nathan
A1  - Eryavec, Goran
SP  - 249
EP  - 253
VL  - 1
IS  - 3
N2  - Buspirone, a nonbenzodiazepine anxiolytic, has been shown to decrease aggression in animal models and reduce agitation in a small number of patients with organic brain syndromes. An open pilot study was conducted to assess the usefulness of buspirone in managing agitation and aggression in elderly dementia patients. Sixteen patients, ages 65-89, with various types of dementia associated with severe agitation and aggression were treated with buspirone. Outcome was measured by the Clinical Global Impression Scale. Significant improvement was noted in six patients. Buspirone holds promise as a modestly effective and relatively safe alternative to neuroleptics in the management of agitation and behavioral disturbances associated with dementia. More systematic trials are indicated.<br><br>Copyright © 1993 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 1064-7481
UR  - http://dx.doi.org/10.1097/00019442-199300130-00010
ID  - ref1
ER  -