TY  - JOUR
PY  - 2017//
TI  - A case of nonfatal intoxication associated with the recreational use of diphenidine
JO  - Journal of forensic sciences
A1  - Gerace, Enrico
A1  - Bovetto, Elena
A1  - Di Corcia, Daniele
A1  - Vincenti, Marco
A1  - Salomone, Alberto
SP  - 1107
EP  - 1111
VL  - 62
IS  - 4
N2  - Diphenidine is a dissociative drug that shows several psychotropic effects including euphoria, shifts in perception of reality, hallucinations, and transient anterograde amnesia. In this study, a case of acute intoxication occurring after diphenidine intake is reported. A 30-year-old Caucasian male was hospitalized after he was found in a confused and agitated state and unable to communicate. The physical examination displayed tachycardia, miotic pupils, and increased both body temperature and respiratory rate. After a liquid-liquid extraction procedure, GC/MS analysis revealed the presence of diphenidine in plasma and urine at concentrations of 308 and 631 ng/mL, respectively. Methylphenidate and diclazepam were also detected in the plasma. The clinical progress of the patient was favorable, and his symptoms were cured with a symptomatic treatment. The combined circumstantial elements and toxicological results of the case reported revealed the occurrence of an acute intoxication ascribable to the recreational abuse of diphenidine.<br><br>© 2017 American Academy of Forensic Sciences.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-1198
UR  - http://dx.doi.org/10.1111/1556-4029.13355
ID  - ref1
ER  -