TY - JOUR PY - 2016// TI - Distractibility in multiple sclerosis: the role of depression JO - Multiple sclerosis journal - experimental, translational and clinical A1 - Patel, Viral P. A1 - Zambrana, Aaron A1 - Walker, Lisa As A1 - Herrmann, Nathan A1 - Swartz, Richard H. A1 - Feinstein, Anthony SP - e2055217316653150 EP - e2055217316653150 VL - 2 IS - N2 - The present study assesses the influence of depression and anxiety on the effects of cognitive distracters in people with multiple sclerosis (MS). Participants completed computerized versions of the Symbol Digit Modalities Test (c-SDMT) with (n = 51) and without (n = 51) auditory distracters. Based on the Hospital Anxiety and Depression Scale (HADS), 29 (28.4%) and 51 (50%) participants were classified as depressed or anxious, respectively. A regression analysis revealed that depression (p = 0.034), not anxiety (p = 0.264), further impaired performance on the c-SDMT, particularly in the presence of distracters. These results suggest that distracter effects are influenced by depression more than anxiety. Given that distracters are ubiquitous in real-world environments, their use in a cognitive assessment adds to the ecological validity of the results.

Language: en

LA - en SN - 2055-2173 UR - http://dx.doi.org/10.1177/2055217316653150 ID - ref1 ER -