TY - JOUR PY - 2018// TI - Preliminary findings of altered functional connectivity of the default mode network linked to functional outcomes one year after pediatric traumatic brain injury JO - Developmental neurorehabilitation A1 - Stephens, Jaclyn A. A1 - Salorio, Cynthia F. A1 - Barber, Anita D. A1 - Risen, Sarah R. A1 - Mostofsky, Stewart H. A1 - Suskauer, Stacy J. SP - 423 EP - 430 VL - 21 IS - 7 N2 - PURPOSE AND METHOD: This study examined functional connectivity of the default mode network (DMN) and examined brain-behavior relationships in a pilot cohort of children with chronic mild to moderate traumatic brain injury (TBI).

RESULTS: Compared to uninjured peers, children with TBI demonstrated less anti-correlated functional connectivity between DMN and right Brodmann Area 40 (BA 40). In children with TBI, more anomalous less anti-correlated) connectivity between DMN and right BA 40 was linked to poorer performance on response inhibition tasks.

CONCLUSION: Collectively, these preliminary findings suggest that functional connectivity between DMN and BA 40 may relate to longterm functional outcomes in chronic pediatric TBI.

Language: en

LA - en SN - 1751-8423 UR - http://dx.doi.org/10.1080/17518423.2017.1338777 ID - ref1 ER -