TY  - JOUR
PY  - 2017//
TI  - Impact of stress in childhood: psychobiological alterations
JO  - Psicothema
A1  - Arias, Jorge L.
A1  - Méndez, Marta
A1  - Banqueri, María
SP  - 
EP  - 
VL  - 29
IS  - 1
N2  - BACKGROUND: An extremely high percentage of children worldwide are exposed to stress from the fi rst months of life. The aim of this review is to bring together the experimental results related to chronic early-life stress in both human and experimental models. <br><br>METHODS: We aimed to achieve our objective via a thorough review of the literature. <br><br>RESULTS: Early-life stress is a challenge for the developing organism and leads to negative effects in the medium and long term. The emotional, cognitive, and behavioral domains are compromised due to alterations produced in the nervous system, with some of the most important being related to the main neurotransmission systems. <br><br>CONCLUSIONS: By using experimental models, it is possible to address the study of the structural and functional changes resulting from early-life stress and, thus, plan intervention and prevention alternatives.     Key words: Development, early-life stress, neurotransmission, child abuse, maternal separation, neglect. </p>    <p>Language: en</p>
LA  - en
SN  - 0214-9915
UR  - http://dx.doi.org/10.7334/psicothema2016.264
ID  - ref1
ER  -