TY - JOUR PY - 2017// TI - The problem of bias in behavioural intervention studies: lessons from the PACE trial JO - Journal of health psychology A1 - Wilshire, Carolyn SP - 1128 EP - 1133 VL - 22 IS - 9 N2 - Geraghty's recent editorial on the PACE trial for chronic fatigue syndrome has stimulated a lively discussion. Here, I consider whether the published claims are justified by the data. I also discuss wider issues concerning trial procedures, researcher allegiance and participant reporting bias. Cognitive behavioural therapy and graded exercise therapy had modest, time-limited effects on self-report measures, but little effect on more objective measures such as fitness and employment status. Given that the trial was non-blinded, and the favoured treatments were promoted to participants as 'highly effective', these effects may reflect participant response bias. In non-blinded trials, the issue of reporting biases deserves greater attention in future.
Language: en
LA - en SN - 1359-1053 UR - http://dx.doi.org/10.1177/1359105317700885 ID - ref1 ER -