TY - JOUR PY - 2017// TI - The interplay of psychosis and victimisation across the life course: a prospective study in the general population JO - Social psychiatry and psychiatric epidemiology A1 - Honings, Steven A1 - Drukker, Marjan A1 - ten Have, Margreet A1 - de Graaf, Ron A1 - Van Dorsselaer, Saskia A1 - van Os, Jim SP - 1363 EP - 1374 VL - 52 IS - 11 N2 - PURPOSE: Psychosis has been associated with adult victimisation. However, it remains unclear whether psychosis predicts incident adult victimisation, or whether adult victimisation predicts incident psychosis. Furthermore, a moderating effect of childhood victimisation on the association between psychosis and adult victimisation has not been investigated.

METHODS: The longitudinal association between baseline psychotic experiences and six-year incidence of adult victimisation was assessed in a prospective general population cohort of 6646 adults using logistic regression analysis. The association between baseline adult victimisation and six-year incidence of psychotic experiences was examined as well. Furthermore, the moderating effect of childhood victimisation on these bidirectional associations was analysed.

RESULTS: Psychotic experiences and childhood victimisation were both associated with an increased risk of incident adult victimisation. However, this was through competing pathways, as suggested by a negative interaction between psychotic experiences and childhood victimisation. Baseline adult victimisation and childhood victimisation both independently increased the risk of incident psychotic experiences, but there was no interaction between adult victimisation and childhood victimisation.

CONCLUSIONS: Psychosis and victimisation are interconnected throughout the life course. Childhood victimisation is connected to psychosis through two pathways: one direct and one indirect through adult victimisation. In individuals without childhood victimisation, psychosis and adult victimisation bidirectionally impact on each other.

Language: en

LA - en SN - 0933-7954 UR - http://dx.doi.org/10.1007/s00127-017-1430-9 ID - ref1 ER -