TY  - JOUR
PY  - 2018//
TI  - Models used in the study of traumatic brain injury
JO  - Reviews in the neurosciences
A1  - Estrada-Rojo, Francisco
A1  - Martínez-Tapia, Ricardo Jesús
A1  - Estrada-Bernal, Francisco
A1  - Martinez-Vargas, Marina
A1  - Perez-Arredondo, Adán
A1  - Flores-Avalos, Luis
A1  - Navarro, Luz
SP  - 139
EP  - 149
VL  - 29
IS  - 2
N2  - Traumatic brain injury (TBI) is a contemporary health problem and a leading cause of mortality and morbidity worldwide. Survivors of TBI frequently experience disabling long-term changes in cognition, sensorimotor function, and personality. A crucial step in understanding TBI and providing better treatment has been the use of models to mimic the event under controlled conditions. Here, we describe the known head injury models, which can be classified as whole animal (in vivo), in vitro, and mathematical models. We will also review the ways in which these models have advanced the knowledge of TBI.<p />  <p>Language: en</p>
LA  - en
SN  - 0334-1763
UR  - http://dx.doi.org/10.1515/revneuro-2017-0028
ID  - ref1
ER  -