TY - JOUR PY - 1982// TI - Suicide transport: destruction of neurons by retrograde transport of ricin, abrin, and modeccin JO - Science A1 - Wiley, R. G. A1 - Blessing, W. W. A1 - Reis, D. J. SP - 889 EP - 890 VL - 216 IS - 4548 N2 - Certain toxic lectins, including ricin, are retrogradely transported along neuronal processes to the cell body where they inactivate ribosomes, resulting in neuronal death. This process of "suicide transport" suggests a powerful new experimental strategy for solving neurobiological problems.

Language: en

LA - en SN - 0036-8075 UR - http://dx.doi.org/ ID - ref1 ER -