TY - JOUR PY - 2017// TI - False acute kidney injury alert due to model car fuel ingestion JO - BMJ case reports A1 - Powell, Darren A1 - Hassall, Louise A1 - Scholes, David A1 - Al-Jubouri, Mohammad SP - ePub EP - ePub VL - 2017 IS - ePub N2 - We report a case of accidental ingestion of model car fuel (Optifuel) resulting in an apparent elevation of serum creatinine of 274 µmol/L (3.1 mg/dL) as measured by the Jaffe (alkaline picrate) reaction, which resulted in an acute kidney injury (AKI) stage 3 alert being reported. Optifuel contains nitromethane, which has been reported to interfere in the Jaffe reaction causing falsely high creatinine measurements. The laboratory staff were vigilant about this potential interfering substance so repeated the analysis of the creatinine using an enzymatic method that showed a markedly lower result of 47 µmol/L (0.5 mg/dL). This report highlights the ability of nitromethane to potentially mimic AKI and the importance of being aware of the limitations of biochemical tests to avoid misinterpretation of results and instigating inappropriate treatment.

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Language: en

LA - en SN - 1757-790X UR - http://dx.doi.org/10.1136/bcr-2017-221134 ID - ref1 ER -