TY - JOUR PY - 2018// TI - Psychogenic non-epileptic seizures in children and adolescents. Part I: diagnostic formulations JO - Clinical child psychology and psychiatry A1 - Kozlowska, Kasia A1 - Chudleigh, Catherine A1 - Cruz, Catherine A1 - Lim, Melissa A1 - McClure, Georgia A1 - Savage, Blanche A1 - Shah, Ubaid A1 - Cook, Averil A1 - Scher, Stephen A1 - Carrive, Pascal A1 - Gill, Deepak SP - 140 EP - 159 VL - 23 IS - 1 N2 - Psychogenic non-epileptic seizures (PNES) are a nonspecific, umbrella category that is used to collect together a range of atypical neurophysiological responses to emotional distress, physiological stressors and danger. Because PNES mimic epileptic seizures, children and adolescents with PNES usually present to neurologists or to epilepsy monitoring units. After a comprehensive neurological evaluation and a diagnosis of PNES, the patient is referred to mental health services for treatment. This study documents the diagnostic formulations - the clinical formulations about the probable neurophysiological mechanisms - that were constructed for 60 consecutive children and adolescents with PNES who were referred to our Mind-Body Rehabilitation Programme for treatment. As a heuristic framework, we used a contemporary reworking of Janet's dissociation model: PNES occur in the context of a destabilized neural system and reflect a release of prewired motor programmes following a functional failure in cognitive-emotional executive control circuitry. Using this framework, we clustered the 60 patients into six different subgroups: (1) dissociative PNES (23/60; 38%), (2) dissociative PNES triggered by hyperventilation (32/60; 53%), (3) innate defence responses presenting as PNES (6/60; 10%), (4) PNES triggered by vocal cord adduction (1/60; 2%), (5) PNES triggered by activation of the valsalva manoeuvre (1/60; 1.5%) and (6) PNES triggered by reflex activation of the vagus (2/60; 3%). As described in the companion article, these diagnostic formulations were used, in turn, both to inform the explanations of PNES that we gave to families and to design clinical interventions for helping the children and adolescents gain control of their PNES.
Language: en
LA - en SN - 1359-1045 UR - http://dx.doi.org/10.1177/1359104517732118 ID - ref1 ER -