TY  - JOUR
PY  - 2017//
TI  - Disrupted executive function and aggression in individuals with a history of adverse childhood experiences: an event-related potential study
JO  - Journal of nervous and mental disease
A1  - Xue, Jiao-Mei
A1  - Lin, Ping-Zhen
A1  - Sun, Ji-Wei
A1  - Cao, Feng-Lin
SP  - 942
EP  - 951
VL  - 205
IS  - 12
N2  - Here, we explored the functional and neural mechanisms underlying aggression related to adverse childhood experiences. We assessed behavioral performance and event-related potentials during a go/no-go and N-back paradigm. The participants were 15 individuals with adverse childhood experiences and high aggression (ACE + HA), 13 individuals with high aggression (HA), and 14 individuals with low aggression and no adverse childhood experiences (control group). The P2 latency (initial perceptual processing) was longer in the ACE + HA group for the go trials. The HA group had a larger N2 (response inhibition) than controls for the no-go trials. Error-related negativity (error processing) in the ACE + HA and HA groups was smaller than that of controls for false alarm go trials. Lastly, the ACE + HA group had shorter error-related negativity latencies than controls for false alarm trials. Overall, our results reveal the neural correlates of executive function in aggressive individuals with ACEs.<p />  <p>Language: en</p>
LA  - en
SN  - 0022-3018
UR  - http://dx.doi.org/10.1097/NMD.0000000000000743
ID  - ref1
ER  -