TY  - JOUR
PY  - 2017//
TI  - Psychiatric comorbidities modify the association between childhood ADHD and risk for suicidality: a population-based longitudinal study
JO  - Journal of attention disorders
A1  - Yoshimasu, Kouichi
A1  - Barbaresi, William J.
A1  - Colligan, Robert C.
A1  - Voigt, Robert G.
A1  - Killian, Jill M.
A1  - Weaver, Amy L.
A1  - Katusic, Slavica K.
SP  - 777
EP  - 786
VL  - 23
IS  - 8
N2  - OBJECTIVE: The objective of this study was to evaluate the effect of psychiatric comorbidities on the association between childhood ADHD and suicidality among adults. <br><br>METHOD: Subjects were recruited from a population-based birth cohort. Participating adult subjects with childhood ADHD and non-ADHD controls were administered a structured psychiatric interview to assess suicidality and psychiatric comorbidities. Associations were assessed using logistic regression. <br><br>RESULTS: Compared with controls, ADHD cases were significantly more likely to meet criteria for suicidality. Subjects with childhood ADHD who met criteria for generalized anxiety disorder had a higher than expected risk of suicidality with an observed odds ratio of 10.94 (95% confidence interval [4.97, 24.08]) compared with an expected odds ratio of 4.86, consistent with a synergistic interaction effect. Significant synergistic interactions were also observed for hypomanic episode and substance-related disorders. <br><br>CONCLUSION: Childhood ADHD is significantly associated with adult suicidal risk. Comorbidity between ADHD and some psychiatric disorders is associated with a higher suicidal risk than expected.<p />  <p>Language: en</p>
LA  - en
SN  - 1087-0547
UR  - http://dx.doi.org/10.1177/1087054717718264
ID  - ref1
ER  -