TY  - JOUR
PY  - 2014//
TI  - Cortisol and IL-6 responses to stress in female children presenting at a sexual abuse clinic
JO  - Journal of child and adolescent trauma
A1  - Muller, Denise
A1  - Errington, Sheri
A1  - Szabo, Christopher Paul
A1  - Pitts, Neville
A1  - Jacklin, Lorna
SP  - 185
EP  - 191
VL  - 7
IS  - 3
N2  - Since adults with histories of sexual abuse as children experience both dysregulation of cortisol and increased inflammatory markers, we hypothesized that plasma cortisol dysregulation and increased plasma IL-6 would be detectable at the first presentation of pre-pubertal girls to a sexual abuse clinic. Following the stressful forensic examination, the 11 patients recruited to the study had significantly different cortisol concentrations (p < 0.0075), depending on whether they resided with family (309 ± 101 nmol/l) or in a children's home (157 ± 38 nmol/l). IL-6 was detected in all patients residing in a children's home, with plasma cortisol and IL-6 being inversely correlated (r = −0.8875). Our study demonstrates an association between decreased cortisol secretion, inflammation, and place of residence in sexually abused girls.<p /> <p>Language: en</p>
LA  - en
SN  - 1936-1521
UR  - http://dx.doi.org/10.1007/s40653-014-0019-7
ID  - ref1
ER  -