TY  - JOUR
PY  - 2017//
TI  - Traumatic exposures, posttraumatic stress disorder, and cognitive functioning in World Trade Center responders
JO  - Alzheimer's and dementia (New York, N. Y.)
A1  - Clouston, Sean
A1  - Pietrzak, Robert H.
A1  - Kotov, Roman
A1  - Richards, Marcus
A1  - Spiro, Avron
A1  - Scott, Stacey
A1  - Deri, Yael
A1  - Mukherjee, Soumyadeep
A1  - Stewart, Candace
A1  - Bromet, Evelyn
A1  - Luft, Benjamin J.
SP  - 593
EP  - 602
VL  - 3
IS  - 4
N2  - INTRODUCTION: This study examined whether World Trade Center (WTC)-related exposures and posttraumatic stress disorder (PTSD) were associated with cognitive function and whether WTC responders' cognition differed from normative data. <br><br>METHODS: A computer-assisted neuropsychological battery was administered to a prospective cohort study of 1193 WTC responders with no history of stroke or WTC-related head injuries. Data were linked to information collected prospectively since 2002. Sample averages were compared to published norms. <br><br>RESULTS: Approximately 14.8% of sampled responders had cognitive dysfunction. WTC responders had worse cognitive function compared to normative data. PTSD symptom severity and working >5 weeks on-site was associated with lower cognition. <br><br>DISCUSSION: Results from this sample highlight the potential for WTC responders to be experiencing an increased burden of cognitive dysfunction and linked lowered cognitive functioning to physical exposures and to PTSD. Future research is warranted to understand the extent to which cognitive dysfunction is evident in neural dysfunction.<p />  <p>Language: en</p>
LA  - en
SN  - 2352-8737
UR  - http://dx.doi.org/10.1016/j.trci.2017.09.001
ID  - ref1
ER  -