TY  - JOUR
PY  - 2018//
TI  - Falls in older adults with multiple myeloma
JO  - European journal of haematology
A1  - Wildes, Tanya M.
A1  - Fiala, Mark A.
SP  - 273
EP  - 278
VL  - 100
IS  - 3
N2  - OBJECTIVE: To examine the prevalence of falls, factors associated with falls and the relationship between falls and survival in older adults with multiple myeloma METHODS: In an analysis of the Surveillance, Epidemiology and End Results (SEER)-Medicare Health Outcomes Survey (MHOS) linked database, we examined 405 older adults with MM and 513 matched non-cancer controls. The primary outcome was self-reported within the past 12 months. Age, race, gender, symptoms and comorbidities were self-reported in the MHOS. Survival was calculated from SEER data RESULTS: Of the patients with MM, 171 were within 1 year of diagnosis (cohort 1) and 234 were ≥1 year post-diagnosis (cohort 2). Patients in cohort 1 and 2 were more likely to have fallen than controls (26% and 33% vs 23%, p=0.012). On multivariate analysis, among patients with myeloma (combined cohorts 1&2), factors associated with falls included self-report of fatigue [aOR 2.52 (95% CI 1.34-4.93)], depression [aOR 1.90 (95% CI 1.14-3.18)], or poorer general health [aOR 1.86 (95% CI 1.05-3.36)]. Falls were not associated with survival CONCLUSIONS: Older adults with MM have a greater prevalence of falls than matched controls. Self- reported fatigue, depression and poorer general health are associated with greater odds of falls. This article is protected by copyright. All rights reserved.<br><br>This article is protected by copyright. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0902-4441
UR  - http://dx.doi.org/10.1111/ejh.13009
ID  - ref1
ER  -