TY  - JOUR
PY  - 2017//
TI  - Factors influencing psychological well-being in patients with Parkinson's disease
JO  - PLoS one
A1  - Nicoletti, Alessandra
A1  - Mostile, Giovanni
A1  - Stocchi, Fabrizio
A1  - Abbruzzese, Giovanni
A1  - Ceravolo, Roberto
A1  - Cortelli, Pietro
A1  - D'Amelio, Marco
A1  - De Pandis, Maria F.
A1  - Fabbrini, Giovanni
A1  - Pacchetti, Claudio
A1  - Pezzoli, Gianni
A1  - Tessitore, Alessandro
A1  - Canesi, Margherita
A1  - Zappia, Mario
SP  - e0189682
EP  - e0189682
VL  - 12
IS  - 12
N2  - BACKGROUND: Both motor and non-motor symptoms could contribute to significant deterioration of psychological well-being in patients with Parkinson's disease (PD). However, its assessment has been only indirectly evaluated using tools based on health-related quality of life (HRQoL), such as the PDQ-39 scale. <br><br>OBJECTIVES: To evaluate psychological well-being in PD using a specific tool of assessment, the Psychological Well-being Scale (PWS), and its clinical correlates. <br><br>METHODS: This article reports data of patients' perception of health state, as measured by means of the PWS, from an epidemiological, cross-sectional study conducted in Italian PD patients (FORTE Study). We tested possible relationship between well-being and clinical characteristics including fatigue, depression, sleep disruption and HRQoL. <br><br>RESULTS: 272 patients completed the PWS questionnaire. Significant and clinically-relevant correlations were found between PWS total score and Parkinson's Fatigue Scale, Beck Depression Inventory, UPDRS Section I, PD Sleep Scale and PDQ-39 for HRQoL scores. Only clinically negligible correlations were found between PWS and motor scores. <br><br>CONCLUSIONS: Non-motor symptoms have a significant impact on psychological well-being in PD patients.<p />  <p>Language: en</p>
LA  - en
SN  - 1932-6203
UR  - http://dx.doi.org/10.1371/journal.pone.0189682
ID  - ref1
ER  -