TY  - JOUR
PY  - 2017//
TI  - Biomechanical characterization of human dura mater
JO  - Journal of the mechanical behavior of biomedical materials
A1  - De Kegel, Dries
A1  - Vastmans, Julie
A1  - Fehervary, Heleen
A1  - Depreitere, Bart
A1  - Vander Sloten, Jos
A1  - Famaey, Nele
SP  - 122
EP  - 134
VL  - 79
IS  - 
N2  - A reliable computational model of the human head is necessary for better understanding of the physical mechanisms of traumatic brain injury (TBI), car-crash investigation, development of protective head gear and advancement of dural replacement materials. The performance and biofidelity of these models depend largely on the material description of the different structures present in the head. One of these structures is the dura mater, the protective layer around the brain. We tested five human dura mater specimens, with samples at different locations, using planar biaxial tests. We describe the resulting stress-strain curves using both the anisotropic Gasser-Ogden-Holzapfel (GOH) model and the isotropic one-term Ogden model. The low-strain section of the curves is also described using a Neo-Hookean formulation. The obtained stress-strain curves reveal highly nonlinear but isotropic behaviour. A significant amount of inter- and intra-specimen variability is noticed, whereby the latter does not seem to be influenced by location. The GOH model achieves the best fit of the individual test data. A simple Neo-Hookean model can only be used with extreme caution, as it does not manage to capture the nonlinear effects present even at low strains.<br><br>Copyright © 2017 Elsevier Ltd. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 1751-6161
UR  - http://dx.doi.org/10.1016/j.jmbbm.2017.12.023
ID  - ref1
ER  -