TY  - JOUR
PY  - 2018//
TI  - Pediatric abusive head trauma in Taiwan: clinical characteristics and risk factors associated with mortality
JO  - Graefe's archive for clinical and experimental ophthalmology
A1  - Wu, An-Lun
A1  - See, Lai-Chu
A1  - Hsia, Shao-Hsuan
A1  - Tu, Hui-Tzu
A1  - Wang, Nan-Kai
A1  - Huang, Jing-Long
A1  - Hwang, Yih-Shiou
A1  - Lai, Chi-Chun
A1  - Wu, Wei-Chi
SP  - 997
EP  - 1003
VL  - 256
IS  - 5
N2  - PURPOSE: To report the clinical characteristics of abusive head trauma (AHT) in Taiwan and identify the risk factors associated with mortality of these patients. <br><br>METHODS: Children with clinically diagnosed AHT from January 1, 2000, to October 31, 2015 were reviewed. The demographic data, clinical features, and associated retinal and radiologic findings were analyzed. The multivariable logistic regression model analysis was performed to identify the risk factors associated with in-hospital mortality. <br><br>RESULTS: A total of 75 children were included. The mean age was 7.31 ± 6.57 months (range, 1-36 months). Retinal hemorrhages were detected in 69 children with AHT (92%). The majority of retinal hemorrhages were characterized by hemorrhagic numbers higher than ten (74.7%), multi-layered (54.7%), and extension beyond the posterior pole to the peripheral retina (73.3%). Twenty children (26.7%) had macular retinoschisis. As a direct result of AHT, ten children died in the hospital (13.3%). Logistic regression showed that respiratory distress or apnea (adjusted odds ratio [OR] = 22.46; 95% confidence interval [CI], 2.24-225.33; P = .0082), vomiting (adjusted OR = 11.94; 95% CI, 1.31-108.403; P = .0276), retinal finding of macular retinoschisis (adjusted OR = 8.9; 95% CI, 1.01-78.65; P = .0493), and the presence of subarachnoid hemorrhage (SAH) (adjusted OR = 15.17; 95% CI, 1.40-64.84; P = .0255) were independently associated with mortality. <br><br>CONCLUSIONS: Respiratory distress or apnea, vomiting, SAH, and macular retinoschisis are independently associated with mortality in abusive head trauma. A complete ophthalmologic examination with the immediate visualization of intraocular injury should be performed to clarify the likelihood of child abuse and predict a potential poor neurologic outcome.<p />  <p>Language: en</p>
LA  - en
SN  - 0721-832X
UR  - http://dx.doi.org/10.1007/s00417-017-3863-y
ID  - ref1
ER  -