TY - JOUR PY - 2018// TI - Risk of erectile dysfunction after traumatic brain injury: a nationwide population-based cohort study in Taiwan JO - American journal of men's health A1 - Yang, Yun-Ju A1 - Chien, Wu-Chien A1 - Chung, Chi-Hsiang A1 - Hong, Kun-Ting A1 - Yu, Yi-Lin A1 - Hueng, Dueng-Yuan A1 - Chen, Yuan-Hao A1 - Ma, Hsin-I A1 - Chang, Hsin-An A1 - Kao, Yu-Chen A1 - Yeh, Hui-Wen A1 - Tzeng, Nian-Sheng SP - 913 EP - 925 VL - 12 IS - 4 N2 - INTRODUCTION: In our study, we aimed to investigate the association between a traumatic brain injury (TBI) and subsequent erectile dysfunction (ED). This is a population-based study using the claims dataset from The National Health Insurance Research Database.

METHODS: We included 72,642 patients with TBI aged over 20 years, retrospectively, selected from the longitudinal health insurance database during 2000-2010, according to the ICD-9-CM. The control group consisted of 217,872 patients without TBI that were randomly chosen from the database at a ratio of 1:3, with age- and index year matched. Cox proportional hazards analysis was used to estimate the association between the TBI and subsequent ED.

RESULTS: After a 10-year follow-up, the incidence rate of ED was higher in the TBI patients when compared with the non-TBI control group (24.66 and 19.07 per 100,000, respectively). Patients with TBI had a higher risk of developing ED than the non-TBI cohort after the adjustment of the confounding factors, such as age, comorbidity, residence of urbanization and locations, seasons, level of care, and insured premiums (adjusted hazard ratio (HR) = 2.569, 95% CI [1.890, 3.492], p <.001).

CONCLUSION: This is the first study using a comprehensive nationwide database to analyze the association of ED and TBI in the Asian population. After adjusted the confounding factors, patients with TBI have a significantly higher risk of developing ED, especially organic ED, than the general population. This finding might remind clinicians that it's crucial in early identification and treatment of ED in post-TBI patients.

Language: en

LA - en SN - 1557-9883 UR - http://dx.doi.org/10.1177/1557988317750970 ID - ref1 ER -