TY - JOUR
PY - 2018//
TI - Suicide risk, temperament traits, and sleep quality in patients with refractory epilepsy
JO - Epilepsy and behavior
A1 - Castro, Sayra Catalina Coral
A1 - Baroni, Gislaine Verginia
A1 - Martins, William Alves
A1 - Palmini, André Luis Fernandes
A1 - Bisol, Luísa Weber
SP - 254
EP - 258
VL - 80
IS -
N2 - OBJECTIVES: The objective of the study was to access the suicide risk (SR) in patients with refractory epilepsy and its association with temperament and sleep quality.
METHODS: A total of 50 consecutive patients referred for epilepsy surgery evaluation in the Porto Alegre Epilepsy Surgery Program were included. All patients had a detailed neurologic and psychiatric evaluation, including video-electroencephalogram (VEEG), high-resolution magnetic ressonance imaging (MRI), and neuropsychologic assessment. In addition, structured questionnaires were applied: module C of the MINI-plus (International Neuropsychiatric Interview-Brazilian version 5.0.0), Affective and Emotional Composite Temperament Scale (AFECTS), and Pittsburgh Sleep Quality Index (PSQI).
RESULTS: Ten patients (20.0%) showed an increased SR. The most frequent location of the epileptic focus was in the temporal lobe (50%; n=25). Final diagnosis on VEEG comprised epilepsy in 74.0% (n=37), psychogenic nonepileptic seizures (PNES) in 8.0% (n=4), and both in 12%. Thirty patients (60.0%) received surgery indication. Mood disorders were the main psychiatric diagnosis, found in 19 subjects (70.4%), with major depressive disorder (MDD) encountered in 15 patients (55.6%). In the group, SR was more frequent in patients with sleep disorders (p=0.001) and elevated scores of high emotional sensitivity (p=0.003).
CONCLUSION: In this cohort of patients with highly refractory epilepsy, there was a significant association between SR, sleep disorders, and high emotional sensitivity. Careful evaluation of these factors should be performed in these patients to fully access SR.
Copyright © 2018 Elsevier Inc. All rights reserved.
Language: en
LA - en SN - 1525-5050 UR - http://dx.doi.org/10.1016/j.yebeh.2018.01.022 ID - ref1 ER -