TY  - JOUR
PY  - 2018//
TI  - A cost-effectiveness analysis of school-based suicide prevention programmes
JO  - European child and adolescent psychiatry
A1  - Ahern, Susan
A1  - Burke, Lee-Ann
A1  - McElroy, Brendan
A1  - Corcoran, Paul
A1  - McMahon, Elaine M.
A1  - Keeley, Helen
A1  - Carli, Vladimir
A1  - Wasserman, Camilla
A1  - Hoven, Christina W.
A1  - Sarchiapone, Marco
A1  - Apter, Alan
A1  - Balazs, Judit
A1  - Banzer, Raphaela
A1  - Bobes, Julio
A1  - Brunner, Romuald
A1  - Cosman, Doina
A1  - Haring, Christian
A1  - Kaess, Michael
A1  - Kahn, Jean-Pierre
A1  - Keresztény, Agnes
A1  - Postuvan, Vita
A1  - Saiz, Pilar A.
A1  - Värnik, Peeter
A1  - Wasserman, Danuta
SP  - 1295
EP  - 1304
VL  - 27
IS  - 10
N2  - Suicide is one of the leading causes of death among young people globally. In light of emerging evidence supporting the effectiveness of school-based suicide prevention programmes, an analysis of cost-effectiveness is required. We aimed to conduct a full cost-effectiveness analysis (CEA) of the large pan-European school-based RCT, Saving and Empowering Young Lives in Europe (SEYLE). The health outcomes of interest were suicide attempt and severe suicidal ideation with suicide plans. Adopting a payer's perspective, three suicide prevention interventions were modelled with a Control over a 12-month time period. Incremental cost-effectiveness ratios (ICERs) indicate that the Youth Aware of Mental Health (YAM) programme has the lowest incremental cost per 1% point reduction in incident for both outcomes and per quality adjusted life year (QALY) gained versus the Control. The ICERs reported for YAM were €34.83 and €45.42 per 1% point reduction in incident suicide attempt and incident severe suicidal ideation, respectively, and a cost per QALY gained of €47,017 for suicide attempt and €48,216 for severe suicidal ideation. Cost-effectiveness acceptability curves were used to examine uncertainty in the QALY analysis, where cost-effectiveness probabilities were calculated using net monetary benefit analysis incorporating a two-stage bootstrapping technique. For suicide attempt, the probability that YAM was cost-effective at a willingness to pay of €47,000 was 39%. For severe suicidal ideation, the probability that YAM was cost-effective at a willingness to pay of €48,000 was 43%. This CEA supports YAM as the most cost-effective of the SEYLE interventions in preventing both a suicide attempt and severe suicidal ideation.Trial registration number DRKS00000214.<p />  <p>Language: en</p>
LA  - en
SN  - 1018-8827
UR  - http://dx.doi.org/10.1007/s00787-018-1120-5
ID  - ref1
ER  -