TY  - JOUR
PY  - 2018//
TI  - Bizarre and scary ECG in yew leaves poisoning: report of successful treatment
JO  - Annals of noninvasive electrocardiology
A1  - Cerrato, Natascia
A1  - Calzolari, Gilberto
A1  - Tizzani, Pietro
A1  - Actis Perinetto, Emma
A1  - Dellavalle, Antonio
A1  - Aluffi, Enzo
SP  - e12535
EP  - e12535
VL  - 23
IS  - 5
N2  - Yew leaves poisoning is a rare life-threatening intoxication, whose diagnosis can be difficult. Initial symptoms are nausea, vomiting, abdominal pain, dizziness, tachycardia, muscle weakness, confusion, beginning within 1 hr from ingestion and followed by bradycardia, ventricular arrhythmias, ventricular fibrillation, severe hypotension, and death. Taxine-derived alkaloids are responsible for the toxicity of the yew leaves, blocking sodium and calcium channels, and causing conduction abnormalities. Because of lack of a specific antidote and limited efficacy of common antiarrhythmic drugs, prompt diagnosis, detoxification measures, and immediate hemodynamic support (also with transvenous cardiac stimulation) are essential.<br><br>© 2018 Wiley Periodicals, Inc.<p />  <p>Language: en</p>
LA  - en
SN  - 1082-720X
UR  - http://dx.doi.org/10.1111/anec.12535
ID  - ref1
ER  -