TY - JOUR
PY - 2018//
TI - Severe methanol poisoning with neurological sequelae: implications for diagnosis and management
JO - Internal medicine journal
A1 - Holt, Nicolette R.
A1 - Nickson, Christopher P.
SP - 335
EP - 339
VL - 48
IS - 3
N2 - A 22-year-old woman presented with methanol toxicity manifesting as headache, reduced conscious state and visual change after consuming home-made grappa. She progressed to a coma with fixed mydriasis and severe acidaemia (pH 6.55). She was treated with empirical antidote administration (intravenous ethanol) and enhanced elimination through haemodialysis. She survived despite her delayed presentation but developed significant neurological sequelae, including visual impairment. We provide an overview of key elements of diagnosis and recent updates in treatment recommendations.
© 2018 Royal Australasian College of Physicians.
Language: en
LA - en SN - 1444-0903 UR - http://dx.doi.org/10.1111/imj.13725 ID - ref1 ER -