TY  - JOUR
PY  - 2018//
TI  - Risk of readmission for suicide attempt after epilepsy hospitalization
JO  - Epilepsy and behavior
A1  - Xu, Kevin Y.
A1  - Rossi, Kyle C.
A1  - Kim, Anna M.
A1  - Jetté, Nathalie
A1  - Yoo, Ji Yeoun
A1  - Hung, Kenneth
A1  - Dhamoon, Mandip S.
SP  - 124
EP  - 130
VL  - 83
IS  - 
N2  - OBJECTIVE: The objective of this study was to examine if epilepsy admissions are associated with a higher readmission risk for suicide attempt, independent of psychiatric comorbidity, compared with index admissions for other medical causes. <br><br>METHODS: The Nationwide Readmissions Database is a nationally representative dataset containing data from roughly 15 million hospital discharges. Analysis of International Classification of Disease Clinical Modification 9 (ICD-9-CM) codes in the year 2013 revealed 58,278 index admissions for epilepsy; this group was compared with admissions for stroke (N=215,821) and common medical causes (N=973,078). Ninety-day readmission rates for suicide attempts were calculated. Cox regression tested for associations between admission type and suicide attempt readmissions up to 1year following index admission. <br><br>RESULTS: There were 402/100,000 readmissions for suicide attempt within 90days from index admission in the group with epilepsy; 43/100,000 in the stroke group; and between 37 and 89/100,000 in the medical group. Unadjusted hazard ratios (HR) for suicide readmissions within 1year in the group with epilepsy compared with the stroke group were 9.61 (95% confidence interval (CI): 7.69-11.90, p<2.0×10<sup>-16</sup>) and 5.02 compared with the medical group (95% CI: 4.40-5.73, p<2.0×10<sup>-</sup><sup>16</sup>). The HR for readmission in the group with epilepsy, after adjustment for sociodemographic and psychiatric variables, were elevated at 4.91 compared with the stroke group (95% CI: 3.83-6.27, p<2.0×10<sup>-16</sup>), and 2.66 compared with the medical group (95% CI: 2.32-3.05, p<2.0×10<sup>-16</sup>). <br><br>CONCLUSION: Independent of psychiatric comorbidities, epilepsy admissions may be independently associated with more than a threefold increased risk of hospital readmission for suicide in the year following index admission in comparison with patients recently hospitalized because of stroke or other common medical disorders.<br><br>Copyright © 2018 Elsevier Inc. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 1525-5050
UR  - http://dx.doi.org/10.1016/j.yebeh.2018.03.037
ID  - ref1
ER  -