TY - JOUR PY - 2018// TI - 2,4-D poisoning: a review with illustration of two cases JO - Tropical doctor A1 - Pannu, Ashok Kumar A1 - Saroch, Atul A1 - Agrawal, Jatin A1 - Sharma, Navneet SP - 366 EP - 368 VL - 48 IS - 4 N2 - 2,4-D (2,4-dichlorphenoxyacetic acid) is a chlorphenoxy group pesticide. Its relative safety and broad leaf selectivity makes it a favourite herbicide of many home gardeners and agricultural workers. Severe systemic toxicity requiring hospital admission and intensive care usually occurs following intentional oral ingestion. 2,4-D poisoning is an under-recognised cause of a potentially lethal toxic syndrome, especially in low- and middle-income countries, where such compounds are widely used in farming and readily available in households. It warrants close monitoring and high-quality supportive care along with plasma alkalinisation or extracorporeal removal of the toxin.  We present a short review on 2,4-D poisoning and describe two illustrative cases with significant oral ingestion resulted in early and rapidly developing systemic toxicity. Both patients were admitted to the intensive care unit; one patient was managed with alkaline diuresis and other case required three sessions of haemodialysis.

Language: en

LA - en SN - 0049-4755 UR - http://dx.doi.org/10.1177/0049475518786834 ID - ref1 ER -