TY - JOUR
PY - 2019//
TI - A cost-effectiveness analysis of a randomized control trial of a tailored, multifactorial program to prevent falls among the community-dwelling elderly
JO - Archives of physical medicine and rehabilitation
A1 - Matchar, David B.
A1 - Eom, Kirsten
A1 - Duncan, Pamela W.
A1 - Lee, Mina
A1 - Sim, Rita
A1 - Sivapragasam, Nirmali R.
A1 - Lien, Christopher T.
A1 - Hock Ong, Marcus Eng
SP - 1
EP - 8
VL - 100
IS - 1
N2 - OBJECTIVE: To perform a cost-effectiveness analysis of a multifactorial, tailored intervention to reduce falls among a heterogeneous group of high-risk elderly.
DESIGN: Randomized control trial SETTINGS: Communities PARTICIPANTS: Adults aged at least 65 years (N=354) seen at the ED for a fall or fall-related injury and discharged home. INTERVENTIONS: The intervention group received a tailored program of physical therapy focused on progressive training in strength, balance, and gait for a period of 3 months. They also received screening and referrals for low vision, polypharmacy, and environmental hazards. The Short Physical Performance Battery (SPPB) test was assessed at regular intervals to allocate participants into either a home-based or group centre-based program. The control group received usual care prescribed by a physician and educational materials on falls prevention. MAIN OUTCOME MEASURES: The incremental cost-effectiveness ratio (ICER) over the 9-month study period based on intervention costs and utility in terms of quality-adjusted life years (QALYs) calculated from EuroQol-5D scores.
RESULTS: The ICER was S$ 120, 667 per QALY gained (S$ 362 / 0.003 QALYs), above benchmark values (S$ 70,000). However, the intervention was more effective and cost-saving among those with SPPB scores of greater than 6 at baseline, higher cognitive function, better vision and no more than 1 fall in the preceding 6 months. The intervention was also cost-effective among those with 0-1 critical comorbidities ($ 22, 646 / QALY).
CONCLUSION: The intervention was, overall, not cost-effective, compared to usual care. However, the program was cost-effective among healthier subgroups, and even potentially cost-saving among individuals with sufficient reserve to benefit.
Copyright © 2018. Published by Elsevier Inc.
Language: en
LA - en SN - 0003-9993 UR - http://dx.doi.org/10.1016/j.apmr.2018.07.434 ID - ref1 ER -