TY  - JOUR
PY  - 2018//
TI  - Cannabis use and suicide attempts among 86,254 adolescents aged 12-15 years from 21 low- and middle-income countries
JO  - European psychiatry
A1  - Carvalho, André F.
A1  - Stubbs, Brendon
A1  - Vancampfort, Davy
A1  - Kloiber, Stefan
A1  - Maes, Michael
A1  - Firth, Joseph
A1  - Kurdyak, Paul A.
A1  - Stein, Dan J.
A1  - Rehm, Jürgen
A1  - Koyanagi, Ai
SP  - 8
EP  - 13
VL  - 56
IS  - 
N2  - BACKGROUND: Evidence suggests that cannabis use may be associated with suicidality in adolescence. Nevertheless, very few studies have assessed this association in low- and middle-income countries (LMICs). In this cross-sectional survey, we investigated the association of cannabis use and suicidal attempts in adolescents from 21 LMICs, adjusting for potential confounders. <br><br>METHOD: Data from the Global school-based Student Health Survey was analyzed in 86,254 adolescents from 21 countries [mean (SD) age = 13.7 (0.9) years; 49.0% girls]. Suicide attempts during past year and cannabis during past month and lifetime were assessed. Multivariable logistic regression analyses were conducted. <br><br>RESULTS: The overall prevalence of past 30-day cannabis use was 2.8% and the age-sex adjusted prevalence varied from 0.5% (Laos) to 37.6% (Samoa), while the overall prevalence of lifetime cannabis use was 3.9% (range 0.5%-44.9%). The overall prevalence of suicide attempts during the past year was 10.5%. Following multivariable adjustment to potential confounding variables, past 30-day cannabis use was significantly associated with suicide attempts (OR = 2.03; 95% CI: 1.42-2.91). Lifetime cannabis use was also independently associated with suicide attempts (OR = 2.30; 95% CI: 1.74-3.04). <br><br>CONCLUSION: Our data indicate that cannabis use is associated with a greater likelihood for suicide attempts in adolescents living in LMICs. The causality of this association should be confirmed/refuted in prospective studies to further inform public health policies for suicide prevention in LMICs.<br><br>Copyright © 2018 Elsevier Masson SAS. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0924-9338
UR  - http://dx.doi.org/10.1016/j.eurpsy.2018.10.006
ID  - ref1
ER  -