TY  - JOUR
PY  - 2019//
TI  - Prediction of major depressive disorder onset in college students
JO  - Depression and anxiety
A1  - Ebert, David D.
A1  - Buntrock, Claudia
A1  - Mortier, Philippe
A1  - Auerbach, Randy
A1  - Weisel, Kiona K.
A1  - Kessler, Ronald C.
A1  - Cuijpers, Pim
A1  - Green, Jennifer G.
A1  - Kiekens, Glenn
A1  - Nock, Matthew K.
A1  - Demyttenaere, Koen
A1  - Bruffaerts, Ronny
SP  - 294
EP  - 304
VL  - 36
IS  - 4
N2  - BACKGROUND: Major depressive disorder (MDD) in college students is associated with substantial burden. AIMS: To assess 1-year incidence of MDD among incoming freshmen and predictors of MDD-incidence in a representative sample of students. <br><br>METHOD: Prospective cohort study of first-year college students (baseline: n = 2,519, 1-year follow-up: n = 958) RESULTS: The incidence of MDD within the first year of college was 6.9% (SE = 0.8). The most important individual-level predictors of onset were prior suicide plans and/or attempts (OR = 9.5). The strongest population-level baseline predictors were history of childhood-adolescent trauma, stressful experience in the past 12 months, parental psychopathology, and other 12-month mental disorder. Multivariate cross-validated prediction (cross-validated AUC = 0.73) suggest that 36.1% of incident MDD cases in a replication sample would occur among the 10% of students at highest predicted risk (24.5% predicted incidence in this highest-risk subgroup). <br><br>CONCLUSIONS: Screening at college entrance is a promising strategy to identify students at risk of MDD onset, which may improve the development and deployment of targeted preventive interventions.<br><br>© 2018 The Authors. Depression and Anxiety published by Wiley Periodicals, Inc.<p />  <p>Language: en</p>
LA  - en
SN  - 1091-4269
UR  - http://dx.doi.org/10.1002/da.22867
ID  - ref1
ER  -