TY - JOUR
PY - 2019//
TI - High risk of suicide in behavioral variant frontotemporal dementia
JO - American journal of Alzheimer's disease and other dementias
A1 - Zucca, Milena
A1 - Rubino, Elisa
A1 - Vacca, Alessandro
A1 - Govone, Flora
A1 - Gai, Annalisa
A1 - De Martino, Paola
A1 - Boschi, Silvia
A1 - Gentile, Salvatore
A1 - Giordana, Maria Teresa
A1 - Rainero, Innocenzo
SP - 265
EP - 271
VL - 34
IS - 4
N2 - AIM:: The purpose of the study was to determine the prevalence of suicidal ideation and attempts in patients with behavioral variant frontotemporal dementia (bvFTD), evaluating possible risk factors for suicidality.
METHODS:: Risk of suicide was assessed using the Scale for Suicide Ideation (SSI) in 35 patients with bvFTD and 25 controls.
RESULTS:: According to SSI, 40% of patients with bvFTD had suicidal ideation in comparison to 8% of controls ( P =.009). Four patients with bvFTD have attempted suicide versus none control ( P =.006). Patients with bvFTD with suicide risk showed higher levels of anxiety, depression, stress, and hopelessness than patients without suicide risk ( P <.001). Patients who attempted suicide were younger and had a longer disease duration than those with only suicide ideation. Intriguingly, 40% of patients with parkinsonism presented high level of suicide ideation.
CONCLUSIONS:: Our findings show that patients with bvFTD have a high risk of suicide. Additional studies in larger populations are needed to confirm our results.
Language: en
LA - en SN - 1533-3175 UR - http://dx.doi.org/10.1177/1533317518817609 ID - ref1 ER -