TY - JOUR PY - 2019// TI - High risk of suicide in behavioral variant frontotemporal dementia JO - American journal of Alzheimer's disease and other dementias A1 - Zucca, Milena A1 - Rubino, Elisa A1 - Vacca, Alessandro A1 - Govone, Flora A1 - Gai, Annalisa A1 - De Martino, Paola A1 - Boschi, Silvia A1 - Gentile, Salvatore A1 - Giordana, Maria Teresa A1 - Rainero, Innocenzo SP - 265 EP - 271 VL - 34 IS - 4 N2 - AIM:: The purpose of the study was to determine the prevalence of suicidal ideation and attempts in patients with behavioral variant frontotemporal dementia (bvFTD), evaluating possible risk factors for suicidality.

METHODS:: Risk of suicide was assessed using the Scale for Suicide Ideation (SSI) in 35 patients with bvFTD and 25 controls.

RESULTS:: According to SSI, 40% of patients with bvFTD had suicidal ideation in comparison to 8% of controls ( P =.009). Four patients with bvFTD have attempted suicide versus none control ( P =.006). Patients with bvFTD with suicide risk showed higher levels of anxiety, depression, stress, and hopelessness than patients without suicide risk ( P <.001). Patients who attempted suicide were younger and had a longer disease duration than those with only suicide ideation. Intriguingly, 40% of patients with parkinsonism presented high level of suicide ideation.

CONCLUSIONS:: Our findings show that patients with bvFTD have a high risk of suicide. Additional studies in larger populations are needed to confirm our results.

Language: en

LA - en SN - 1533-3175 UR - http://dx.doi.org/10.1177/1533317518817609 ID - ref1 ER -