TY  - JOUR
PY  - 2019//
TI  - Prevalence and phenomenology of violent ideation and behavior among 200 young people at clinical high-risk for psychosis: an emerging model of violence and psychotic illness
JO  - Neuropsychopharmacology
A1  - Brucato, Gary
A1  - Appelbaum, Paul S.
A1  - Masucci, Michael D.
A1  - Rolin, Stephanie A.
A1  - Wall, Melanie M.
A1  - Levin, Mark
A1  - Altschuler, Rebecca
A1  - First, Michael B.
A1  - Lieberman, Jeffrey A.
A1  - Girgis, Ragy R.
SP  - 907
EP  - 914
VL  - 44
IS  - 5
N2  - In a previously reported longitudinal study of violent ideation (VI) and violent behavior (VB) among 200 youths at clinical high-risk (CHR) for psychosis, we found that VI, hitherto underinvestigated, strongly predicted transition to first-episode psychosis (FEP) and VB, in close temporal proximity. Here, we present participants' baseline characteristics, examining clinical and demographic correlates of VI and VB. These participants, aged 13-30, were examined at Columbia University Medical Center's Center of Prevention and Evaluation, using clinical interviews and the structured interview for psychosis-risk syndromes (SIPS). At the onset of our longitudinal study, we gathered demographics, signs and symptoms, and descriptions of VI and VB. One-third of participants reported VI (n = 65, 32.5%) at baseline, experienced as intrusive and ego-dystonic, and associated with higher suspiciousness and overall positive symptoms. Less than one-tenth reported VB within 6 months of baseline (n = 17, 8.5%), which was unrelated to SIPS-positive symptoms, any DSM diagnosis or other clinical characteristic. The period from conversion through post-FEP stabilization may be characterized by heightened risk of behavioral disinhibition and violence. We provide a preliminary model of how violence risk may peak at various points in the course of psychotic illness.<p />  <p>Language: en</p>
LA  - en
SN  - 0893-133X
UR  - http://dx.doi.org/10.1038/s41386-018-0304-5
ID  - ref1
ER  -