TY - JOUR PY - 2018// TI - A systematic review of etiological risk factors associated with early mortality among National Football League players JO - Orthopaedic journal of sports medicine A1 - Owora, Arthur H. A1 - Kmush, Brittany L. A1 - Walia, Bhavneet A1 - Sanders, Shane SP - e2325967118813312 EP - e2325967118813312 VL - 6 IS - 12 N2 - BACKGROUND: Multiple risks predispose professional football players to adverse health outcomes and, in extreme cases, early death; however, our understanding of etiological risk factors related to early mortality is limited.

PURPOSE: To identify etiological risk factors associated with all-cause and cause-specific mortality among National Football League (NFL) players. STUDY DESIGN: Systematic review; Level of evidence, 3.

METHODS: Articles examining all-cause and cause-specific mortality risk factors among previous NFL players were identified by systematically searching: PubMed, PsycINFO, Web of Science, and Google Scholar from 1990 to 2017. Study eligibility and quality were evaluated using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.

RESULTS: A total of 801 nonduplicated studies were identified through our search strategy. Of these, 9 studies examining 11 different risk factors were included in the systematic review. Overall, the risk of all-cause and cause-specific mortality was lower among NFL players than among the general male population in the United States. Nonwhite athletes, those in power positions, and those with a high playing-time body mass index (≥30 kg/m2) were associated with elevated all-cause and cardiovascular mortality risks.

CONCLUSION: Methodological issues associated with the examined all-cause and cause-specific mortality risk factors preclude a definitive conclusion of etiological protective or risk effects. Comparison groups less prone to selection bias ("healthy worker effect") and a life-course approach to the evaluation of suspected risk factors are warranted to identify etiological factors associated with early mortality among NFL players.

Language: en

LA - en SN - 2325-9671 UR - http://dx.doi.org/10.1177/2325967118813312 ID - ref1 ER -