TY  - JOUR
PY  - 2019//
TI  - Acute neurologic injury in children admitted to the cardiac intensive care unit
JO  - Annals of thoracic surgery
A1  - Bell, Jamie L.
A1  - Saenz, Lucas
A1  - Domnina, Yuliya
A1  - Baust, Tracy
A1  - Panigrahy, Ashok
A1  - Bell, Michael J.
A1  - Camprubí-Camprubí, Marta
A1  - Sanchez-de-Toledo, Joan
SP  - 1831
EP  - 1837
VL  - 107
IS  - 6
N2  - BACKGROUND: Children with both acquired and congenital heart disease have low mortality but increased risk of neurologic morbidity which is multi-factorial. We hypothesize that acute neurologic injuries contributes to mortality in such children and are an important cause of death. <br><br>METHODS: Retrospective review of all admissions to the pediatric cardiac intensive care unit from January 2011 through January 2015. Patients were assessed for any acute neurologic events during admission (ANE) as defined by radiologic findings or electrographic seizures. <br><br>RESULTS: Of all 1,573 children admitted to the CICU, Incidence of ANE was 8.6%. Mortality of the ANE group was 16.3% compared to 1.5% who did not have ANE. Odds ratio for mortality with ANE was 8.55 (CI 4.56-16.03). Patients with ANE had a longer hospital length of stay compared to those without (41.4 ± 4 vs 14.2 ± 0.6 days (p<0.001)). Need for ECMO, previous cardiac arrest and prematurity were independently associated with presence of an acute neurologic event. <br><br>CONCLUSIONS: Neurologic injuries are common in pediatric cardiac intensive cares and are associated with an increase in mortality and hospital length of stay. Children admitted to the CICU are likely to benefit from improved surveillance and neuroprotective strategies to prevent neurological mortality.<br><br>Copyright © 2019. Published by Elsevier Inc.<p />  <p>Language: en</p>
LA  - en
SN  - 0003-4975
UR  - http://dx.doi.org/10.1016/j.athoracsur.2018.12.027
ID  - ref1
ER  -