TY  - JOUR
PY  - 2019//
TI  - Effects of the interaction between genetic factors and maltreatment on child and adolescent psychiatric disorders
JO  - Psychiatry research
A1  - Carvalho, Carolina Muniz
A1  - Pan, Pedro M.
A1  - Ota, Vanessa K.
A1  - Spindola, Letícia M.
A1  - Xavier, Gabriela
A1  - Santoro, Marcos L.
A1  - Mazzotti, Diego R.
A1  - Pellegrino, Renata
A1  - Hakonarson, Hakon
A1  - Rohde, Luis Augusto Paim
A1  - Miguel, Eurípedes Constantino
A1  - Gadelha, Ary
A1  - Bressan, Rodrigo Affonseca
A1  - Belangero, Sintia I.
SP  - 575
EP  - 577
VL  - 273
IS  - 
N2  - We evaluated the effects of the interaction between child maltreatment (CM) and single nucleotide polymorphisms (SNPs) on development of mental disorders (MD) and psychopathology. We genotyped 720 individuals from a Brazilian community school-based prospective study, focusing on SNPs in 21 genes known to be associated with mental disorders. CM was assessed via a multi-informant-measure, which was previously validated. To test G × CM, we used linear or logistic models depending on variable evaluated (MD or dimensional psychopathology). After Bonferroni multiple comparison correction, we did not find any statistically significant association of G × CM with either MD or psychopathology.<br><br>Copyright © 2019. Published by Elsevier B.V.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-1781
UR  - http://dx.doi.org/10.1016/j.psychres.2019.01.078
ID  - ref1
ER  -